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20 Jan 2021

A 2017 study found that Americans’ exposure to glyphosate increased approximately 500 percent since Roundup Ready GMO crops were introduced in the U.S in 1996. There are many ways consumers are exposed to Roundup on a daily basis, from ingesting food treated with glyphosate, to visiting a local park where glyphosate was sprayed, to handling the product itself. International Life Sciences Institute (ILSI) is a Food Industry Lobby Group, Nebraska regulatory documents regarding AltEn neonicotinoid contamination, New glyphosate papers point to “urgency” for more research on chemical impact to human health, New research adds evidence that weed killer glyphosate disrupts hormones. These assessments consider epidemiological, toxicology and genotoxicity studies. Several organizations have evaluated cancer risks associated with glyphosate in recent years. These studies are used to conduct formal risk assessments that quantify the likelihood of adverse effects to humans using toxicological data and models of exposure. The Food Quality Protection Act (FQPA, passed in 1996) requires a “reasonable certainty that no harm will result from aggregate exposure" to pesticides and establishes enforceable residue standards based on models of food consumption. The USDA Food and Drug Administration actively monitors the level of glyphosate on foods in the marketplace. Right to Know show the agency had planned to start testing over 300 samples of corn syrup for glyphosate in April 2017. The decade’s long orchestration to downplay the health risks of glyphosate in the food supply is losing its grip. The IARC Working Group also conducted an objective statistical analysis of the results of all of the available studies on glyphosate and non-Hodgkin lymphoma, which included the AHS and all of the case– control studies. Therefore, the risk of a hazardous effect to human health is a function of the toxicity of the chemical and the likelihood of exposure to a biologically relevant dose. Glyphosate does not degrade quickly in plants. This practice, known as desiccation, may be a significant source of dietary exposure to glyphosate. A review of the risk assessment process for evaluating the potential of glyphosate to cause adverse effects on human health. In April 2019, the EPA reaffirmed its position that glyphosate poses no risk to public health. Monsanto influence in research: In March 2017, the federal court judge unsealed some internal Monsanto documents that raised new questions about Monsanto’s influence on the EPA process and about the research regulators rely on. Channa Jayasumana and Sarath Gunatilake, the 2019 Award for Scientific Freedom and Responsibility for their work to “investigate a possible connection between glyphosate and chronic kidney disease under challenging circumstances.” The scientists have reported that glyphosate plays a key role in transporting heavy metals to the kidneys of those drinking contaminated water, leading to high rates of chronic kidney disease in farming communities. Glyphosate was first registered in the United States in 1974 as the active ingredient in Roundup but is now available in many commercial herbicide products. June 2020 paper published in Environmental Pollution. Glyphosate products can be safely used by following label directions. Chronic toxicity describes the hazard associated with long term exposure to a chemical, such as repeated ingestion of low doses in food residues. Based on review of epidemiological studies, the EPA found no evidence of association between glyphosate exposure and numerous cancer outcomes but indicated more data was needed to determine association between glyphosate exposure and Non-Hodgkin Lymphoma2. Glyphosate is degraded in soil and water by microbes and binds tightly to soil particles, which prevents leaching of glyphosate into ground water. Although the acute toxic effects of glyphosate and AMPA on mammals are low, there are animal data raising the possibility of health effects associated with chronic, ultra-low doses related to accumulation of these compounds in the environment. Health Canada says glyphosate is not a risk to human health when used according to label directions. The first three trials ended in large awards to plaintiffs for liability and damages, with juries ruling that Monsanto’s weed killer was a substantial contributing factor in causing them to develop NHL. Some farmers use glyphosate on non-GMO crops such as wheat, barley, oats, and lentils to dry down the crop ahead of harvest in order to accelerate the harvest. The team of international scientists found there was a particular association between glyphosate and non-Hodgkin lymphoma. People are beginning to question the painted image of glyphosate as a benign, environment-friendly, and non-toxic herbicide. Before the suspension, one FDA chemist found alarming levels of glyphosate in many samples of U.S. honey, levels that were technically illegal because there have been no allowable levels established for honey by the EPA. The major health risk identified was until recently concern over stomach bacteria. European Union: The European Food Safety Authority and the European Chemicals Agency have said glyphosate is not likely to be carcinogenic to humans. The vast majority of glyphosate is applied to fallow fields or in crops that are used for animal feed (corn, soybean), energy (corn) or fiber (cotton) and is applied early in the growing season to young vegetative crops many weeks before plants produce grain or are harvested. Health 1Kniss, A (2017) Long term trends in the intensity and relative toxicity of herbicide use. July 2020 paper published in Molecular and Cellular Endocrinology. In 2016, the EPA evaluated the carcinogenic potential of glyphosate and concluded that glyphosate was “not likely to be carcinogenic to humans at doses relevant to human health risk assessments". Why do we need this? The USDA quietly dropped a plan to start testing food for residues of glyphosate in 2017. In December 2016, the EPA convened a Scientific Advisory Panel to review the report; members were divided in their assessment of EPA’s work, with some finding the EPA erred in how it evaluated certain research. The documents suggest that Monsanto’s long-standing claims about the safety of glyphosate and Roundup do not necessarily rely on sound science as the company asserts, but on efforts to manipulate the science. In 2015, the World Health Organization's International Agency for Research on Cancer (IARC) concluded that “Glyphosate is probably carcinogenic to humans". Evaluates the risks to human health and the environment posed by glyphosate, a post-emergent, systemic, and non-selective herbicide used, primarily against deep-rooted perennial species, in agriculture and forestry, and for weed-killing in water systems, parks, road verges, and gardens. June 2020 paper published in Veterinary and Animal Science. Glyphosate Risks To Human Health Ignored: Where Is The Duty Of Care? At an impressive 257 pages, the fully-referenced report comprehensively covers both the cancer and non-cancer health effects linked to glyphosate exposure, the … Glyphosate is the chemical that is a herbicide commonly known as “Round Up”. The World Health Organization's International Agency for Research on Cancer (IARC) says the chemical is … Glyphosate also has lower chronic toxicity to humans than 90% of all herbicides1. See papers in  SpringerPlus (2015), BMC Nephrology (2015), Environmental Health (2015), International Journal of Environmental Research and Public Health (2014). Humans. Adverse health effects from acute poisoning events will be dose-related. July 2020 study in the journal Toxicology and Applied Pharmacology. The glyphosate molecule (below) is unique among herbicides. By entering your email, you consent to receive communications from Penn State Extension. All chemicals, including herbicides, are potentially hazardous to human health. But is it really harmless? 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